Symbol
Name
ID

Tbr1
T-box brain transcription factor 1
MGI:107404

Phenotype annotations related to nervous system

Darker colors indicate more annotations

Mouse Phenotypes

spina bifida

abnormal olfactory bulb development

abnormal brain interneuron morphology

decreased brain size

abnormal anterior commissure morphology

abnormal forebrain morphology

abnormal amygdala morphology

abnormal olfactory bulb interneuron morphology

abnormal olfactory bulb external plexiform layer morphology

abnormal olfactory bulb tufted cell morphology

abnormal olfactory bulb glomerular layer morphology

abnormal olfactory bulb mitral cell layer morphology

abnormal mitral cell morphology

olfactory bulb hypoplasia

abnormal olfactory cortex morphology

abnormal olfactory tract morphology

abnormal innervation

abnormal neuron physiology

increased excitatory postsynaptic current frequency

increased miniature inhibitory postsynaptic current frequency

Availability

Mouse Genotype

Tbr1^{tm1.1(KOMP)Mbp}/Tbr1^{tm1.1(KOMP)Mbp}

Tbr1^tm1Jlr/Tbr1^tm1Jlr

Tbr1^tm1Jlr/Tbr1^tm1Jlr
Tg(Mbp-MAPT/EGFP)#Eja/0

Tbr1^{tm1.1(KOMP)Mbp}/Tbr1⁺

Tbr1^tm1.1Csbd/Tbr1⁺

Tbr1^tm1Jlr/Tbr1⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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